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CAS NO.520-27-4
Diosmin 520-27-4
EP6.0 or Diosmin:Hesperidine=90:10(micronized powder)or as per the client`s requirement including microbiology
Diosmin 520-27-4
EP6.0 or Diosmin:Hesperidine=90:10 (micronized powder) or as per the client`s requirement including microbiology
Description of diosmin:
Raw material:Hesperidoside
CAS NO: 520-27-4 Formula: C28H32O15, Molecular Weight:608.54
Application and actions:
It is used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins. As a flav
onoid, it also has anti-inflammatory, free-radical scavenging, and antimutagenic properties.
We can according to the client'S specific requirements: microbiological (no irradiation),color, heavy metals` requirements under EU rules no 629/2008
DMF under preparation
What is Diosmin?
Diosmin is a semisynthetic drug (modified hesperidin), a member of the flavonoid family. It is an oral phlebotropic
drug used in the treatment of venous disease, i.e., chronic venous insufficiency (CVI) and hemorrhoidal disease
(HD), in acute or chronic hemorrhoids, in place of rubber-band ligation, in combination with fiber supplement,
or as an adjuvant therapy to hemorrhoidectomy, in order to reduce secondary bleeding. To control internal
symptoms of hemorrhoids (piles), it is used with hesperidin.
Where will Diosmin be used for?
Diosmin is currently a prescription medication in some European countries, and is sold as a nutritional supplement
in the United States and the rest of Europe. Diosmin aglycone is diosmetin.
Diosmin has been found to be effective in mitigating hyperglycemia in diabetic rats. It is also speculated that diosmin
might have potential in the treatment of neurodegenerative diseases, such as alzheimer's disease, and its
anti-inflammatory and anti-apoptotic activity has been demonstrated in neuronal cells, in vitro.